CLEC10A

Across TCGA cell cohorts, CLEC10A RNA expression is significantly associated with the go_rna of many other GO terms, with 503 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLEC10A-associated GO terms across cancer lineages are Triglyceride-rich lipoprotein particle remodeling, Positive regulation of protein localization to chromatin, and Chylomicron remodeling. Each is linked with CLEC10A in more than 3 cancer types. Because this analysis shows association rather than direction, both CLEC10A-to-partner and partner-to-CLEC10A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Triglyceride-rich lipoprotein particle remodeling grouped by CLEC10A-low versus CLEC10A-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLEC10A→partner) and Y-score (partner→CLEC10A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Triglyceride-rich lipoprotein particle remodeling →	+0.940	+0.208	.009	.009	3	4
SKIN	Positive regulation of protein localization to chromatin →	-0.174	-0.018	<.001	.001	3	3
LIVER	Chylomicron remodeling →	+2.145	+0.398	<.001	.001	3	3
BLOOD_Leukemia	Negative regulation of plasma membrane bounded cell projection assembly →	-0.025	-0.335	.003	.008	3	2
BLOOD_Leukemia	Organic acid transport →	+0.022	+0.464	<.001	.009	3	2
LIVER	Biotin transport →	+0.254	+0.268	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 503 associations by consensus.

Triglyceride-rich lipoprotein particle remodeling by CLEC10A expression — LIVER

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