Across TCGA patient cohorts, CLDN9 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,582 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CLDN9-associated proteins across cancer lineages are ACSF2, TTC38, and PPL. Each is linked with CLDN9 in more than 4 cancer types. Because this analysis shows association rather than direction, both CLDN9-to-partner and partner-to-CLDN9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN9→partner) and Y-score (partner→CLDN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACSF2 →	+0.508	+0.530	<.001	.006	3	5
UCEC	TTC38 →	-0.464	-0.789	<.001	.003	3	4
COAD	PPL →	+0.594	+0.724	<.001	.001	3	4
OV	MBD2 →	-0.203	-1.207	.002	<.001	3	4
LSCC	ARFGAP1 →	+0.186	+0.568	<.001	<.001	3	3
LUAD	PARD6B_S11 →	+0.533	+0.978	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,582 associations by consensus.

Exploration

CLDN9 survival (RNA) · tumor vs normal (RNA) · all CLDN9 data types