CLDN9

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLDN9 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLDN9-associated genes across cancer lineages are eIF4E, SCD, and Bax. Each is linked with CLDN9 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDN9-to-partner and partner-to-CLDN9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN9→partner) and Y-score (partner→CLDN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECeIF4E →+0.327+3.000.007.03731
UCECSCD →-0.163-2.986.010.03731
UCECBax →+0.292+3.000.035.03731
UCECSF2 →-0.202-2.986.001.03721
UCECTIGAR →+0.200+3.026.023.01921
UCECDJ-1 →+0.297+3.000.002.03721
Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

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