Across TCGA cell cohorts, CLDN9 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,036 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CLDN9-associated GO terms across cancer lineages are Membrane assembly, Membrane biogenesis, and Xenobiotic metabolic process. Each is linked with CLDN9 in more than 10 cancer types. Because this analysis shows association rather than direction, both CLDN9-to-partner and partner-to-CLDN9 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN9→partner) and Y-score (partner→CLDN9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Membrane assembly →	+0.105	+1.732	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Membrane biogenesis →	+0.095	+1.199	<.001	.001	3	10
OESOPHAGUS	Xenobiotic metabolic process →	-0.114	-2.293	.003	<.001	3	10
OESOPHAGUS	Small GTPase-mediated signal transduction →	+0.088	+2.171	.001	.002	3	10
OVARY	Negative regulation of tumor necrosis factor superfamily cytokine production →	+0.104	+1.300	<.001	<.001	3	10
STOMACH	Maintenance of unfolded protein →	+0.173	+1.590	<.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,036 associations by consensus.

Exploration

CLDN9 survival (RNA) · tumor vs normal (RNA) · all CLDN9 data types