Across TCGA pan-cancer cohorts, CLDN7P1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated CLDN7P1 data layer.
The strongest signal is observed in kidney chromophobe (KICH), where higher CLDN7P1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLDN7P1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.
KICH, LIHC, and ACC are the cancer types where CLDN7P1 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.