CLDN7

Across TCGA cell cohorts, CLDN7 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLDN7-associated genes across cancer lineages are IL20. Each is linked with CLDN7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDN7-to-partner and partner-to-CLDN7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL20 grouped by CLDN7-low versus CLDN7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN7→partner) and Y-score (partner→CLDN7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IL20 →	+0.216	+3.662	<.001	.009	2	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

IL20 by CLDN7 expression — LARGE_INTESTINE

Explore this box plot interactively →