Across TCGA patient cohorts, CLDN6 protein abundance is significantly associated with the RNA expression of many other genes, with 1,328 significant associations in total. OV shows the largest number of these associations.

The most reproducible CLDN6-associated genes across cancer lineages are TNFRSF10A, ATP6V1B2, and TNFRSF10A-AS1. Each is linked with CLDN6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDN6-to-partner and partner-to-CLDN6 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN6→partner) and Y-score (partner→CLDN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TNFRSF10A →	-1.161	-2.845	.001	.003	3	2
OV	ATP6V1B2 →	-0.489	-0.856	<.001	.003	3	2
OV	TNFRSF10A-AS1 →	-0.888	-1.587	<.001	<.001	3	2
LUAD	UNG →	+0.621	+2.144	.002	.003	3	2
LUAD	SMC1B →	+1.512	+2.417	<.001	<.001	3	2
OV	CRYL1 →	-0.740	-1.320	.004	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,328 associations by consensus.

Exploration

CLDN6 survival (RNA) · tumor vs normal (RNA) · all CLDN6 data types