Across TCGA cell cohorts, CLDN6 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,439 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible CLDN6-associated GO terms across cancer lineages are Regulatory ncRNA-mediated gene silencing, Positive regulation of cytoplasmic translation, and Sodium ion transport. Each is linked with CLDN6 in more than 5 cancer types. Because this analysis shows association rather than direction, both CLDN6-to-partner and partner-to-CLDN6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN6→partner) and Y-score (partner→CLDN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulatory ncRNA-mediated gene silencing →	+0.061	+2.272	<.001	.003	3	6
SKIN	Positive regulation of cytoplasmic translation →	+0.077	+0.243	<.001	.007	3	5
OVARY	Sodium ion transport →	-0.076	-2.577	<.001	.001	3	5
BONE	Negative regulation of myoblast fusion →	+0.109	+0.339	<.001	<.001	3	5
OVARY	Regulation of norepinephrine secretion →	-0.854	-2.189	<.001	.001	3	5
BONE	Import across plasma membrane →	-0.068	-0.292	<.001	<.001	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,439 associations by consensus.

Exploration

CLDN6 survival (RNA) · tumor vs normal (RNA) · all CLDN6 data types