CLDN34

Across TCGA patient cohorts, CLDN34 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,972 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CLDN34-associated GO terms across cancer lineages are Establishment of pigment granule localization, Dendrite development, and Apical protein localization. Each is linked with CLDN34 in more than 16 cancer types. Because this analysis shows association rather than direction, both CLDN34-to-partner and partner-to-CLDN34 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of pigment granule localization grouped by CLDN34-low versus CLDN34-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN34→partner) and Y-score (partner→CLDN34) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Establishment of pigment granule localization →	+0.040	+0.127	<.001	<.001	3	17
STAD	Dendrite development →	+0.036	+0.130	<.001	<.001	3	16
THYM	Apical protein localization →	+0.073	+0.168	<.001	.001	2	17
STAD	Regulation of dendrite development →	+0.038	+0.136	<.001	<.001	3	16
THYM	Pigment accumulation →	+0.063	+0.235	<.001	<.001	3	15
STAD	Pigment granule localization →	+0.041	+0.143	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,972 associations by consensus.

Establishment of pigment granule localization by CLDN34 expression — STAD

Explore this box plot interactively →