Across TCGA cell cohorts, CLDN25 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLDN25-associated genes across cancer lineages are PRR27. Each is linked with CLDN25 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDN25-to-partner and partner-to-CLDN25 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN25→partner) and Y-score (partner→CLDN25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRR27 →	+0.197	+4.054	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Exploration

CLDN25 survival (RNA) · tumor vs normal (RNA) · all CLDN25 data types