Across TCGA patient cohorts, CLDN24 RNA expression is significantly associated with the RNA expression of many other genes, with 10,334 significant associations in total. KIRP shows the largest number of these associations.

The most reproducible CLDN24-associated genes across cancer lineages are WWC2, MARK3, and RBAK. Each is linked with CLDN24 in more than 18 cancer types. Because this analysis shows association rather than direction, both CLDN24-to-partner and partner-to-CLDN24 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN24→partner) and Y-score (partner→CLDN24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	WWC2 →	+1.697	+0.438	<.001	<.001	3	19
ESCA	MARK3 →	+0.645	+0.486	<.001	<.001	2	17
KIRP	RBAK →	+0.817	+0.180	<.001	<.001	3	16
ESCA	COL27A1 →	+1.296	+0.566	<.001	<.001	3	15
SCLC	CENPJ →	+0.794	+0.463	<.001	.001	3	15
ESCA	FER →	+0.627	+0.401	<.001	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,334 associations by consensus.

Exploration

CLDN24 survival (RNA) · tumor vs normal (RNA) · all CLDN24 data types