Across TCGA patient cohorts, CLDN24 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,942 significant associations in total. STAD shows the largest number of these associations.

The most reproducible CLDN24-associated GO terms across cancer lineages are Monoubiquitinated protein deubiquitination, Protein K63-linked ubiquitination, and Regulation of cilium assembly. Each is linked with CLDN24 in more than 16 cancer types. Because this analysis shows association rather than direction, both CLDN24-to-partner and partner-to-CLDN24 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN24→partner) and Y-score (partner→CLDN24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Monoubiquitinated protein deubiquitination →	+0.119	+0.568	<.001	<.001	3	17
STAD	Protein K63-linked ubiquitination →	+0.051	+0.064	<.001	<.001	3	16
STAD	Regulation of cilium assembly →	+0.040	+0.055	<.001	<.001	3	16
STAD	Regulation of proteolysis involved in protein catabolic process →	+0.052	+0.057	<.001	<.001	3	16
STAD	Modulation by host of symbiont process →	+0.046	+0.071	<.001	<.001	3	15
STAD	Protein modification by small protein removal →	+0.049	+0.086	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,942 associations by consensus.

Exploration

CLDN24 survival (RNA) · tumor vs normal (RNA) · all CLDN24 data types