CLDN20

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CLDN20 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLDN20-associated genes across cancer lineages are pDC. Each is linked with CLDN20 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDN20-to-partner and partner-to-CLDN20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by CLDN20-low versus CLDN20-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN20→partner) and Y-score (partner→CLDN20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECpDC →+0.062+2.818.039.03721
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

pDC by CLDN20 expression — UCEC

Box plot of pDC in CLDN20-low vs CLDN20-high samples in UCEC.

Explore this box plot interactively →

Exploration