CLDN19

Across TCGA patient cohorts, CLDN19 protein abundance is significantly associated with the RNA expression of many other genes, with 467 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CLDN19-associated genes across cancer lineages are APOBEC3H, RIN3, and TNFSF13B. Each is linked with CLDN19 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLDN19-to-partner and partner-to-CLDN19 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLDN19 versus APOBEC3H in CCRCC, with a Pearson correlation of -0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN19→partner) and Y-score (partner→CLDN19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	APOBEC3H →	-2.123	-0.526	.005	.005	3	1
CCRCC	RIN3 →	-0.619	-0.452	<.001	.001	3	1
CCRCC	TNFSF13B →	-1.442	-0.452	.002	.001	3	1
CCRCC	HERC1 →	-0.522	-0.452	.001	.001	3	1
CCRCC	BMF →	-0.963	-0.452	.004	.001	3	1
CCRCC	LILRA1 →	-0.963	-0.569	.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 467 associations by consensus.

CLDN19 vs APOBEC3H — CCRCC

Explore this scatter interactively →