CLDN19

Across TCGA cell cohorts, CLDN19 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,002 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CLDN19-associated GO terms across cancer lineages are Protein localization to cytoplasmic stress granule, Regulation of calcium ion transport into cytosol, and Regulation of chromatin organization. Each is linked with CLDN19 in more than 5 cancer types. Because this analysis shows association rather than direction, both CLDN19-to-partner and partner-to-CLDN19 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cytoplasmic stress granule grouped by CLDN19-low versus CLDN19-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN19→partner) and Y-score (partner→CLDN19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Protein localization to cytoplasmic stress granule →	+0.091	+0.010	<.001	.003	3	6
BONE	Regulation of calcium ion transport into cytosol →	-0.162	-0.023	.001	.002	3	5
BONE	Regulation of chromatin organization →	+0.068	+0.021	.007	.006	3	5
BONE	Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.073	+0.021	.004	.006	3	5
BONE	Ribosomal protein import into nucleus →	+0.051	+0.022	.008	.004	3	5
BREAST	Nuclear transport →	+0.079	+0.038	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,002 associations by consensus.

Protein localization to cytoplasmic stress granule by CLDN19 expression — BLOOD_Lymphoma

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