CLDN14

Across TCGA patient cohorts, CLDN14 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,752 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CLDN14-associated proteins across cancer lineages are TGFBI, P4HA2, and PLOD2. Each is linked with CLDN14 in more than 6 cancer types. Because this analysis shows association rather than direction, both CLDN14-to-partner and partner-to-CLDN14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLDN14 versus TGFBI in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN14→partner) and Y-score (partner→CLDN14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TGFBI →	+0.798	+0.593	<.001	<.001	3	7
GBM	P4HA2 →	+0.818	+0.322	<.001	<.001	3	7
GBM	PLOD2 →	+0.858	+0.295	<.001	<.001	3	7
OV	ITGA5 →	+0.598	+0.228	.002	.008	3	7
OV	MXRA5 →	+0.740	+0.184	.001	.008	3	6
BRCA	PLOD1 →	+0.606	+0.479	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,752 associations by consensus.

CLDN14 vs TGFBI — LSCC

Explore this scatter interactively →