CLDN14

Across TCGA cell cohorts, CLDN14 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,209 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLDN14-associated GO terms across cancer lineages are PML body organization, Wound healing, and Actin filament bundle assembly. Each is linked with CLDN14 in more than 8 cancer types. Because this analysis shows association rather than direction, both CLDN14-to-partner and partner-to-CLDN14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PML body organization grouped by CLDN14-low versus CLDN14-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN14→partner) and Y-score (partner→CLDN14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	PML body organization →	+0.148	+0.271	<.001	.001	3	9
SOFT_TISSUE	Wound healing →	+0.121	+0.326	<.001	.001	3	8
OESOPHAGUS	Actin filament bundle assembly →	+0.094	+0.168	.006	.007	3	8
OVARY	Regulation of calcium ion transport into cytosol →	+0.188	+0.226	<.001	.007	2	8
BLOOD_Lymphoma	Cytoplasmic pattern recognition receptor signaling pathway →	+0.074	+1.364	<.001	<.001	3	7
LIVER	Actin filament bundle organization →	+0.100	+2.166	.005	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,209 associations by consensus.

PML body organization by CLDN14 expression — OVARY

Explore this box plot interactively →