CLDN12

Across TCGA cell cohorts, CLDN12 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,031 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CLDN12-associated GO terms across cancer lineages are Receptor metabolic process, Cilium-dependent cell motility, and Cilium or flagellum-dependent cell motility. Each is linked with CLDN12 in more than 9 cancer types. Because this analysis shows association rather than direction, both CLDN12-to-partner and partner-to-CLDN12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Receptor metabolic process grouped by CLDN12-low versus CLDN12-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN12→partner) and Y-score (partner→CLDN12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Receptor metabolic process →	+0.070	+1.633	<.001	<.001	3	10
SOFT_TISSUE	Cilium-dependent cell motility →	-0.067	-0.595	<.001	.001	3	10
SOFT_TISSUE	Cilium or flagellum-dependent cell motility →	-0.067	-0.595	<.001	.001	3	10
BREAST	Peptidyl-serine modification →	+0.066	+0.795	.004	.002	2	10
SOFT_TISSUE	Vesicle fusion with Golgi apparatus →	+0.105	+0.841	<.001	<.001	3	9
STOMACH	Sperm motility →	-0.077	-1.252	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,031 associations by consensus.

Receptor metabolic process by CLDN12 expression — STOMACH

Explore this box plot interactively →