CLDN11

Across TCGA cell cohorts, CLDN11 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,544 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CLDN11-associated GO terms across cancer lineages are Intracellular transport of virus, Response to water, and Transport of virus. Each is linked with CLDN11 in more than 8 cancer types. Because this analysis shows association rather than direction, both CLDN11-to-partner and partner-to-CLDN11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intracellular transport of virus grouped by CLDN11-low versus CLDN11-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLDN11→partner) and Y-score (partner→CLDN11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Intracellular transport of virus →	+0.179	+1.742	<.001	.006	3	9
BONE	Response to water →	+0.177	+3.196	<.001	<.001	3	9
BREAST	Transport of virus →	+0.179	+1.742	<.001	.006	3	9
BONE	Positive regulation of cell-substrate junction organization →	+0.164	+2.671	<.001	<.001	3	8
BREAST	Aorta smooth muscle tissue morphogenesis →	+1.353	+1.857	<.001	.001	2	9
BONE	Positive regulation of cell-substrate adhesion →	+0.178	+2.809	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,544 associations by consensus.

Intracellular transport of virus by CLDN11 expression — BREAST

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