CLCN6

Across TCGA patient cohorts, CLCN6 RNA expression is significantly associated with the RNA expression of many other genes, with 20,982 significant associations in total. ACC shows the largest number of these associations.

The most reproducible CLCN6-associated genes across cancer lineages are TNRC6B, STK4, and ADNP. Each is linked with CLCN6 in more than 33 cancer types. Because this analysis shows association rather than direction, both CLCN6-to-partner and partner-to-CLCN6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLCN6 versus TNRC6B in DLBC, with a Pearson correlation of 0.81.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCN6→partner) and Y-score (partner→CLCN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	TNRC6B →	+1.123	+0.984	<.001	<.001	3	34
DLBC	STK4 →	+1.164	+0.913	<.001	<.001	3	34
DLBC	ADNP →	+1.323	+0.977	<.001	<.001	3	34
DLBC	SMCHD1 →	+1.496	+0.868	<.001	<.001	3	34
ACC	TSC2 →	+0.987	+1.006	<.001	<.001	3	34
KICH	USP42 →	+0.994	+0.888	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,982 associations by consensus.

CLCN6 vs TNRC6B — DLBC

Explore this scatter interactively →