CLCN3

Across TCGA patient cohorts, CLCN3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,041 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible CLCN3-associated proteins across cancer lineages are ARFIP1, LRBA, and TRIM2. Each is linked with CLCN3 in more than 7 cancer types. Because this analysis shows association rather than direction, both CLCN3-to-partner and partner-to-CLCN3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CLCN3 versus ARFIP1 in UCEC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCN3→partner) and Y-score (partner→CLCN3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARFIP1 →	+0.412	+0.673	<.001	<.001	3	8
BRCA	LRBA →	+0.480	+0.723	<.001	<.001	3	7
LUAD	TRIM2 →	+0.682	+0.501	<.001	<.001	3	6
LSCC	GALNT7 →	+0.518	+0.457	<.001	<.001	3	6
GBM	PTPRC →	-0.542	-0.442	.004	<.001	2	6
PDAC	SCOC →	+0.415	+0.387	.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,041 associations by consensus.

CLCN3 vs ARFIP1 — UCEC

Explore this scatter interactively →