Across TCGA patient cohorts, CLCN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,103 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLCN1-associated GO terms across cancer lineages are Monosaccharide metabolic process, Response to endoplasmic reticulum stress, and Lamellipodium organization. Each is linked with CLCN1 in more than 15 cancer types. Because this analysis shows association rather than direction, both CLCN1-to-partner and partner-to-CLCN1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCN1→partner) and Y-score (partner→CLCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Monosaccharide metabolic process →	+0.046	+0.257	<.001	<.001	3	16
STAD	Response to endoplasmic reticulum stress →	+0.038	+0.229	<.001	<.001	3	16
STAD	Lamellipodium organization →	+0.045	+0.238	<.001	<.001	3	15
STAD	Biological process involved in interaction with host →	+0.045	+0.245	<.001	<.001	3	15
STAD	Response to starvation →	+0.061	+0.383	<.001	<.001	3	15
STAD	Activation of cysteine-type endopeptidase activity involved in apoptotic process →	+0.039	+0.266	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,103 associations by consensus.

Exploration

CLCN1 survival (RNA) · tumor vs normal (RNA) · all CLCN1 data types