CLCC1

Across TCGA pan-cancer cohorts, CLCC1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CLCC1 data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CLCC1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated CLCC1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where CLCC1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	II,III,IV	0.139	0.979	.001	45	view →
PDAC	DFS	Tertile	All	0.298	0.457	.016	20	view →
HNSC	OS	Tertile	II,III,IV	0.848	0.584	.005	15	view →
LSCC	DFS	Median	All	0.912	0.460	.007	10	view →
GBM	OS	Quartile	All	0.677	0.948	.013	6	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CLCC1–CCRCC (DFS)

Open the CCRCC breakdown →