CLCA2

Across TCGA cell cohorts, CLCA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,277 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CLCA2-associated GO terms across cancer lineages are Transepithelial water transport, Phylloquinone catabolic process, and Vitamin K catabolic process. Each is linked with CLCA2 in more than 5 cancer types. Because this analysis shows association rather than direction, both CLCA2-to-partner and partner-to-CLCA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transepithelial water transport grouped by CLCA2-low versus CLCA2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CLCA2→partner) and Y-score (partner→CLCA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Transepithelial water transport →	+2.277	+2.081	<.001	.003	3	6
OESOPHAGUS	Phylloquinone catabolic process →	+1.248	+2.377	.001	.004	3	6
OESOPHAGUS	Vitamin K catabolic process →	+1.248	+2.377	.001	.004	3	6
SKIN	Morula formation →	+1.076	+0.475	<.001	<.001	2	6
LUNG_NSCLC_LUAD	Glycosphingolipid catabolic process →	+0.073	+0.611	.006	.008	3	5
BLOOD_Leukemia	Hematopoietic or lymphoid organ development →	+0.055	+0.042	.006	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,277 associations by consensus.

Transepithelial water transport by CLCA2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →