CLBA1

Across TCGA patient cohorts, CLBA1 mutation is significantly associated with the RNA expression of many other genes, with 941 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLBA1-associated genes across cancer lineages are TRAJ5, RNU1-19P, and RN7SKP12. Each is linked with CLBA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLBA1-to-partner and partner-to-CLBA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ5 grouped by CLBA1-low versus CLBA1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLBA1→partner) and Y-score (partner→CLBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TRAJ5 →	+0.728	+2.458	<.001	<.001	3	2
HNSC	RNU1-19P →	+0.220	+4.578	<.001	.008	3	2
COAD	RN7SKP12 →	+0.193	+5.734	<.001	<.001	3	2
COAD	RNU6-1234P →	+0.278	+4.547	.006	.005	3	2
HNSC	MIR664A →	+0.452	+5.008	<.001	.004	3	1
SKCM	SUMO2P16 →	+0.195	+4.730	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 941 associations by consensus.

TRAJ5 by CLBA1 expression — UCEC

Explore this box plot interactively →