CLBA1

Across TCGA cell cohorts, CLBA1 mutation is significantly associated with the RNA expression of many other genes, with 20 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLBA1-associated genes across cancer lineages are ZBTB47, KCNQ4, and NEDD1. Each is linked with CLBA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLBA1-to-partner and partner-to-CLBA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZBTB47 grouped by CLBA1-low versus CLBA1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLBA1→partner) and Y-score (partner→CLBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZBTB47 →	+0.916	+3.299	.004	.004	2	1
LARGE_INTESTINE	KCNQ4 →	+1.002	+3.212	<.001	.006	2	1
LARGE_INTESTINE	NEDD1 →	+0.594	+3.212	.004	.006	2	1
LARGE_INTESTINE	RGS10 →	+1.000	+3.212	.004	.006	2	1
LARGE_INTESTINE	MCOLN2 →	+1.380	+3.212	.006	.006	2	1
LARGE_INTESTINE	ZUP1 →	+0.609	+3.212	.006	.006	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

ZBTB47 by CLBA1 expression — LARGE_INTESTINE

Explore this box plot interactively →