CLASP2

Across TCGA cell cohorts, CLASP2 mutation is significantly associated with the RNA expression of many other genes, with 487 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CLASP2-associated genes across cancer lineages are MYH1, MYH4, and MTFMT. Each is linked with CLASP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CLASP2-to-partner and partner-to-CLASP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYH1 grouped by CLASP2-low versus CLASP2-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLASP2→partner) and Y-score (partner→CLASP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	MYH1 →	+0.029	+5.000	<.001	.006	3	2
PANCREAS	MYH4 →	+0.026	+5.000	<.001	.006	3	2
LARGE_INTESTINE	MTFMT →	+0.545	+2.459	<.001	.006	3	2
LARGE_INTESTINE	CRACD →	+0.973	+2.458	<.001	<.001	3	2
LARGE_INTESTINE	MMACHC →	+0.709	+2.807	<.001	<.001	3	2
LARGE_INTESTINE	EAF1 →	+0.424	+1.949	.002	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 487 associations by consensus.

MYH1 by CLASP2 expression — PANCREAS

Explore this box plot interactively →