CLASP1

Across TCGA pan-cancer cohorts, CLASP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CLASP1 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CLASP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CLASP1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and HNSC show a favorable association.

CCRCC, LSCC, and PDAC are the cancer types where CLASP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	All	0.584	1.000	<.001	48	view →
LSCC	DFS	Tertile	II,III,IV	0.939	0.445	<.001	44	view →
PDAC	OS	Quartile	All	0.809	0.899	.022	9	view →
HNSC	DFS	Tertile	II,III,IV	0.923	0.755	.047	1	view →
GBM	DFS	Median	All	0.809	0.686	.047	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CLASP1–CCRCC (OS)

Open the CCRCC breakdown →