CLASP1

Across TCGA patient cohorts, CLASP1 mutation is significantly associated with the RNA expression of many other genes, with 7,962 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CLASP1-associated genes across cancer lineages are COMMD9, NSUN4, and CNOT9. Each is linked with CLASP1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CLASP1-to-partner and partner-to-CLASP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, COMMD9 grouped by CLASP1-low versus CLASP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CLASP1→partner) and Y-score (partner→CLASP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	COMMD9 →	+0.330	+1.451	<.001	<.001	3	4
UCEC	NSUN4 →	+0.225	+2.271	.006	<.001	3	4
UCEC	CNOT9 →	+0.348	+1.606	<.001	<.001	3	4
COAD	CHCHD4 →	+0.400	+1.947	<.001	.009	3	4
SKCM	CHRNA5 →	+0.595	+2.341	.001	.003	3	4
SKCM	POLD3 →	+0.518	+3.527	.002	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,962 associations by consensus.

COMMD9 by CLASP1 expression — UCEC

Explore this box plot interactively →