CKS2

Across TCGA patient cohorts, CKS2 protein abundance is significantly associated with the protein abundance of many other proteins, with 8,303 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CKS2-associated proteins across cancer lineages are CDK1, KIF22, and UBE2T. Each is linked with CKS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CKS2-to-partner and partner-to-CKS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CKS2 versus CDK1 in UCEC, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CKS2→partner) and Y-score (partner→CKS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDK1 →	+0.778	+0.784	<.001	<.001	3	5
UCEC	KIF22 →	+0.642	+0.520	<.001	<.001	3	5
GBM	UBE2T →	+0.727	+0.511	.001	<.001	3	4
UCEC	DLGAP5 →	+0.831	+0.803	<.001	<.001	3	4
UCEC	NCAPG →	+0.581	+0.559	<.001	<.001	3	4
UCEC	DNMT1_S154 →	+1.098	+0.524	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,303 associations by consensus.

CKS2 vs CDK1 — UCEC

Explore this scatter interactively →