CKS2

Across TCGA cell cohorts, CKS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,142 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CKS2-associated GO terms across cancer lineages are Positive regulation of chromosome condensation, Immunoglobulin heavy chain V-D-J recombination, and CENP-A containing chromatin assembly. Each is linked with CKS2 in more than 18 cancer types. Because this analysis shows association rather than direction, both CKS2-to-partner and partner-to-CKS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of chromosome condensation grouped by CKS2-low versus CKS2-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKS2→partner) and Y-score (partner→CKS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Positive regulation of chromosome condensation →	+0.225	+1.163	<.001	.001	3	19
LUNG_NSCLC_LUSC	Immunoglobulin heavy chain V-D-J recombination →	+0.221	+1.460	<.001	.002	3	19
BLOOD_Myeloma	CENP-A containing chromatin assembly →	+0.223	+1.403	<.001	.001	3	18
BLOOD_Myeloma	Establishment of meiotic spindle orientation →	+0.140	+1.212	.008	.001	3	18
BLOOD_Myeloma	Regulation of mitotic nuclear division →	+0.127	+1.256	.001	.006	3	17
BLOOD_Myeloma	Chromosome localization →	+0.111	+1.391	.002	.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,142 associations by consensus.

Positive regulation of chromosome condensation by CKS2 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →