CKS1BP6

Across TCGA patient cohorts, CKS1BP6 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,435 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CKS1BP6-associated GO terms across cancer lineages are CENP-A containing chromatin assembly, Attachment of spindle microtubules to kinetochore, and Regulation of mitotic cell cycle spindle assembly checkpoint. Each is linked with CKS1BP6 in more than 16 cancer types. Because this analysis shows association rather than direction, both CKS1BP6-to-partner and partner-to-CKS1BP6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENP-A containing chromatin assembly grouped by CKS1BP6-low versus CKS1BP6-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKS1BP6→partner) and Y-score (partner→CKS1BP6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	CENP-A containing chromatin assembly →	+0.074	+0.303	<.001	<.001	3	17
STAD	Attachment of spindle microtubules to kinetochore →	+0.064	+0.171	<.001	<.001	3	17
STAD	Regulation of mitotic cell cycle spindle assembly checkpoint →	+0.049	+0.197	<.001	<.001	3	17
STAD	Mitotic spindle elongation →	+0.087	+0.249	<.001	<.001	3	16
STAD	Centromere complex assembly →	+0.059	+0.232	<.001	<.001	3	16
STAD	Spindle elongation →	+0.091	+0.253	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,435 associations by consensus.

CENP-A containing chromatin assembly by CKS1BP6 expression — ESCA

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