CKM

Across TCGA pan-cancer cohorts, CKM Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated CKM data layer compared with 28 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher CKM Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CKM expression acts as an unfavorable survival marker.

LIHC and BLCA are the cancer types where CKM Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	OS	Median	All	0.181	0.707	.004	9	view →
BLCA	OS	Median	III,IV	0.117	0.684	<.001	6	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

CKM–LIHC (OS)

Open the LIHC breakdown →