Q-omics provides the consensus-scored CKBP1 profile across patient tissues and cancer cell-line models. CKBP1 expression is associated with patient survival in 17 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, CKBP1 is differentially expressed in 4, with the highest sampling consensus in LUAD. Additionally, CKBP1 RNA expression shows 6,454 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight KICH, LUAD, and STAD as cancer lineages where CKBP1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CKBP1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CKBP1 survival associations across molecular data types. CKBP1 RNA expression shows survival associations in the most cancer types (17). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CKBP1 RNA expression–survival associations across cancer types. High CKBP1 expression shows unfavorable associations in KICH, KIRC, SKCM and UVM, but favorable associations in STAD and COAD. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KICH as the clearest survival context for CKBP1 RNA expression.
This table summarizes CKBP1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for CKBP1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CKBP1 shows lower tumor expression in KIRP and KICH and higher tumor expression in LUAD and COAD. The LUAD box plot shows higher CKBP1 RNA expression in tumor versus normal tissue (log2 FC = +0.041, t-test p < 0.001).
This table shows molecular features associated with CKBP1 in patient tissues and cancer cell lines. In patient samples, CKBP1 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
