CKAP4

Across TCGA pan-cancer cohorts, CKAP4 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CKAP4 data layer compared with 28 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CKAP4 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CKAP4 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

CCRCC, PDAC, and HNSC are the cancer types where CKAP4 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.727	0.935	.006	22	view →
PDAC	DFS	Median	All	0.678	0.843	.003	19	view →
HNSC	DFS	Median	IV	0.861	0.698	.023	10	view →
GBM	DFS	Quartile	All	0.723	0.893	.007	7	view →
LSCC	DFS	Tertile	II,III,IV	0.540	0.820	.042	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CKAP4–CCRCC (OS)

Open the CCRCC breakdown →