CKAP4

Across TCGA cell cohorts, CKAP4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,212 significant associations in total. CNS shows the largest number of these associations.

The most reproducible CKAP4-associated GO terms across cancer lineages are Vesicle cargo loading, Regulation of protein exit from endoplasmic reticulum, and Positive regulation of actin filament bundle assembly. Each is linked with CKAP4 in more than 13 cancer types. Because this analysis shows association rather than direction, both CKAP4-to-partner and partner-to-CKAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Vesicle cargo loading grouped by CKAP4-low versus CKAP4-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKAP4→partner) and Y-score (partner→CKAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Vesicle cargo loading →	+0.111	+1.446	<.001	.001	3	14
BONE	Regulation of protein exit from endoplasmic reticulum →	+0.164	+1.375	<.001	<.001	3	13
BONE	Positive regulation of actin filament bundle assembly →	+0.182	+1.052	<.001	<.001	3	12
SKIN	Positive regulation of protein exit from endoplasmic reticulum →	+0.121	+1.378	<.001	<.001	3	12
BONE	Collagen metabolic process →	+0.238	+0.972	<.001	<.001	3	12
SOFT_TISSUE	COPII-coated vesicle cargo loading →	+0.121	+1.434	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,212 associations by consensus.

Vesicle cargo loading by CKAP4 expression — BREAST

Explore this box plot interactively →