CKAP2

Across TCGA pan-cancer cohorts, CKAP2 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CKAP2 data layer compared with 29 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CKAP2 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CKAP2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

LUAD, HNSC, and LSCC are the cancer types where CKAP2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	II,III,IV	0.912	0.321	.002	15	view →
HNSC	OS	Median	All	0.499	0.979	.020	13	view →
LSCC	DFS	Quartile	All	0.680	0.207	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CKAP2–LUAD (DFS)

Open the LUAD breakdown →