CKAP2

Across TCGA patient cohorts, CKAP2 mutation is significantly associated with the RNA expression of many other genes, with 3,896 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CKAP2-associated genes across cancer lineages are ARPP19P2, RNU6-1068P, and GSTA9P. Each is linked with CKAP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CKAP2-to-partner and partner-to-CKAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ARPP19P2 grouped by CKAP2-low versus CKAP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CKAP2→partner) and Y-score (partner→CKAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ARPP19P2 →	+0.137	+1.588	.008	.006	3	3
BRCA	RNU6-1068P →	+0.290	+3.531	.001	.008	3	2
BRCA	GSTA9P →	+0.497	+3.462	<.001	.006	3	2
LUAD	MIR3143 →	+1.023	+4.194	<.001	.009	3	2
UCEC	MTATP6P21 →	+0.220	+1.719	<.001	.006	3	2
UCEC	TSPY12P →	+0.008	+3.834	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,896 associations by consensus.

ARPP19P2 by CKAP2 expression — UCEC

Explore this box plot interactively →