CKAP2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CKAP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,105 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CKAP2-associated GO terms across cancer lineages are Regulation of mitotic nuclear division, Regulation of mitotic sister chromatid separation, and Regulation of nuclear division. Each is linked with CKAP2 in more than 19 cancer types. Because this analysis shows association rather than direction, both CKAP2-to-partner and partner-to-CKAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic nuclear division grouped by CKAP2-low versus CKAP2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CKAP2→partner) and Y-score (partner→CKAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BREASTRegulation of mitotic nuclear division →+0.127+1.232<.001<.001320
BREASTRegulation of mitotic sister chromatid separation →+0.186+1.276<.001<.001320
BREASTRegulation of nuclear division →+0.126+1.232<.001<.001320
BREASTMitotic metaphase chromosome alignment →+0.122+1.075<.001<.001319
LUNG_NSCLC_LUSCProtein localization to chromosome, centromeric region →+0.168+0.917.002<.001319
BREASTRegulation of spindle checkpoint →+0.188+1.321<.001<.001319
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,105 associations by consensus.

Regulation of mitotic nuclear division by CKAP2 expression — BREAST

Box plot of Regulation of mitotic nuclear division in CKAP2-low vs CKAP2-high samples in BREAST.

Explore this box plot interactively →

Exploration