CIZ1

Across TCGA patient cohorts, CIZ1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,328 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CIZ1-associated proteins across cancer lineages are PRPF4, FUBP3, and WDR5. Each is linked with CIZ1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CIZ1-to-partner and partner-to-CIZ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CIZ1 versus PRPF4 in GBM, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CIZ1→partner) and Y-score (partner→CIZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PRPF4 →	+0.259	+0.316	<.001	<.001	3	6
LSCC	FUBP3 →	+0.203	+0.553	<.001	<.001	3	6
GBM	WDR5 →	+0.288	+0.371	<.001	<.001	3	6
PDAC	SPIN1_S199 →	+0.755	+0.326	.001	<.001	3	6
LSCC	DHX9 →	+0.294	+0.662	<.001	<.001	3	6
GBM	EHMT1 →	+0.329	+0.363	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,328 associations by consensus.

CIZ1 vs PRPF4 — GBM

Explore this scatter interactively →