CIZ1

Across TCGA patient cohorts, CIZ1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,088 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CIZ1-associated genes across cancer lineages are RBM18, XPA, and GAPVD1. Each is linked with CIZ1 in more than 5 cancer types. Because this analysis shows association rather than direction, both CIZ1-to-partner and partner-to-CIZ1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CIZ1 versus RBM18 in BRCA, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CIZ1→partner) and Y-score (partner→CIZ1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RBM18 →	+0.502	+0.229	<.001	<.001	3	6
LSCC	XPA →	+0.645	+0.274	<.001	<.001	3	6
HNSC	GAPVD1 →	+0.442	+0.245	<.001	<.001	3	6
BRCA	TSC1 →	+0.747	+0.292	<.001	<.001	3	6
BRCA	ZBTB26 →	+0.632	+0.302	<.001	<.001	3	6
HNSC	STKLD1 →	+0.522	+0.208	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,088 associations by consensus.

CIZ1 vs RBM18 — BRCA

Explore this scatter interactively →