CITED4

Across TCGA patient cohorts, CITED4 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,850 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible CITED4-associated proteins across cancer lineages are KLC3_S466, BNIP1, and CHD8_S1978. Each is linked with CITED4 in more than 3 cancer types. Because this analysis shows association rather than direction, both CITED4-to-partner and partner-to-CITED4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CITED4 versus KLC3_S466 in LSCC, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CITED4→partner) and Y-score (partner→CITED4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KLC3_S466 →	+0.619	+0.682	<.001	<.001	3	4
OV	BNIP1 →	-0.623	-1.974	.008	.008	3	3
OV	CHD8_S1978 →	+0.637	+1.274	<.001	.003	3	3
OV	CLASP2_S459 →	-1.035	-1.546	<.001	<.001	3	3
UCEC	CLMN →	+0.423	+1.107	.003	.002	3	3
PDAC	ZBTB46_S168 →	-0.921	-0.648	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,850 associations by consensus.

CITED4 vs KLC3_S466 — LSCC

Explore this scatter interactively →