CITED4

Across TCGA patient cohorts, CITED4 protein abundance is significantly associated with the RNA expression of many other genes, with 767 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CITED4-associated genes across cancer lineages are RN7SL221P, KATNAL1, and PLLP. Each is linked with CITED4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CITED4-to-partner and partner-to-CITED4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CITED4 versus RN7SL221P in BRCA, with a Pearson correlation of -0.33.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CITED4→partner) and Y-score (partner→CITED4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL221P →	-0.932	-0.364	<.001	.005	3	2
BRCA	KATNAL1 →	+0.647	+0.488	.001	<.001	3	1
BRCA	PLLP →	+0.722	+0.460	.001	.001	3	1
BRCA	MYEF2 →	+1.146	+0.553	.001	.005	3	1
BRCA	KANK1 →	+1.105	+0.597	.001	.001	3	1
BRCA	ACCS →	+0.899	+0.420	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 767 associations by consensus.

CITED4 vs RN7SL221P — BRCA

Explore this scatter interactively →