CITED4

Across TCGA cell cohorts, CITED4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,647 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CITED4-associated GO terms across cancer lineages are Regulation of receptor clustering, Regulation of tumor necrosis factor production, and Regulation of myoblast fusion. Each is linked with CITED4 in more than 8 cancer types. Because this analysis shows association rather than direction, both CITED4-to-partner and partner-to-CITED4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of receptor clustering grouped by CITED4-low versus CITED4-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CITED4→partner) and Y-score (partner→CITED4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of receptor clustering →	+0.165	+1.565	<.001	<.001	3	9
STOMACH	Regulation of tumor necrosis factor production →	+0.062	+2.250	.002	<.001	3	9
LARGE_INTESTINE	Regulation of myoblast fusion →	+0.043	+0.782	.002	.002	3	8
STOMACH	Cell-substrate adhesion →	+0.115	+1.999	<.001	<.001	3	8
SOFT_TISSUE	Glial cell differentiation →	+0.051	+0.967	.008	<.001	2	8
STOMACH	Cell-substrate junction organization →	+0.212	+2.259	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,647 associations by consensus.

Regulation of receptor clustering by CITED4 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →