CITED2

Across TCGA patient cohorts, CITED2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,112 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CITED2-associated proteins across cancer lineages are SP100_S171, PPIF, and UTRN. Each is linked with CITED2 in more than 4 cancer types. Because this analysis shows association rather than direction, both CITED2-to-partner and partner-to-CITED2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CITED2 versus SP100_S171 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CITED2→partner) and Y-score (partner→CITED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	SP100_S171 →	+0.795	+0.706	<.001	<.001	3	5
LSCC	PPIF →	-0.417	-0.462	<.001	<.001	3	5
BRCA	UTRN →	+0.330	+0.779	<.001	<.001	3	4
COAD	VIM →	+0.376	+0.621	<.001	<.001	3	4
LUAD	ZNF318_S2101 →	-0.818	-0.498	.006	.005	3	4
CCRCC	CAST_S440 →	+0.644	+0.743	<.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,112 associations by consensus.

CITED2 vs SP100_S171 — LSCC

Explore this scatter interactively →