CITED2

Across TCGA patient cohorts, CITED2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,164 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CITED2-associated genes across cancer lineages are POLDIP3, CRYM, and FOLR1. Each is linked with CITED2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CITED2-to-partner and partner-to-CITED2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CITED2 versus POLDIP3 in CCRCC, with a Pearson correlation of 0.73.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CITED2→partner) and Y-score (partner→CITED2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	POLDIP3 →	+0.955	+1.080	.003	<.001	3	2
CCRCC	CRYM →	+1.922	+1.047	.005	.001	3	2
CCRCC	FOLR1 →	+1.383	+0.661	.005	.001	3	2
CCRCC	PCGF1 →	+0.395	+0.683	.001	<.001	3	2
CCRCC	TRIP10 →	+1.550	+0.722	<.001	.002	3	2
CCRCC	A4GALT →	+2.379	+0.867	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,164 associations by consensus.

CITED2 vs POLDIP3 — CCRCC

Explore this scatter interactively →