CITED1

Across TCGA patient cohorts, CITED1 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,102 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CITED1-associated GO terms across cancer lineages are Negative regulation of B cell proliferation, Mesenchymal stem cell proliferation, and Multi-pass transmembrane protein insertion into ER membrane. Each is linked with CITED1 in more than 11 cancer types. Because this analysis shows association rather than direction, both CITED1-to-partner and partner-to-CITED1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of B cell proliferation grouped by CITED1-low versus CITED1-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CITED1→partner) and Y-score (partner→CITED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Negative regulation of B cell proliferation →	-0.141	-1.810	<.001	<.001	3	11
LGG	Mesenchymal stem cell proliferation →	+0.084	+1.302	<.001	<.001	3	10
UVM	Multi-pass transmembrane protein insertion into ER membrane →	+0.062	+1.461	<.001	<.001	3	10
UCEC	Skeletal muscle atrophy →	-0.065	-0.512	<.001	<.001	2	11
LAML	Striated muscle atrophy →	-0.057	-0.215	.009	.009	1	12
SARC	Positive regulation of neuron projection arborization →	+0.043	+0.855	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,102 associations by consensus.

Negative regulation of B cell proliferation by CITED1 expression — SCLC

Explore this box plot interactively →