CITED1

Across TCGA cell cohorts, CITED1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,981 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CITED1-associated GO terms across cancer lineages are Response to interleukin-9, Microtubule-based transport, and Positive regulation of complement activation. Each is linked with CITED1 in more than 8 cancer types. Because this analysis shows association rather than direction, both CITED1-to-partner and partner-to-CITED1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to interleukin-9 grouped by CITED1-low versus CITED1-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CITED1→partner) and Y-score (partner→CITED1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Response to interleukin-9 →	-0.276	-1.460	<.001	<.001	3	9
LARGE_INTESTINE	Microtubule-based transport →	+0.021	+1.200	.002	<.001	3	8
OVARY	Positive regulation of complement activation →	-1.739	-1.490	<.001	<.001	3	8
LUNG_SCLC	Cytoplasmic pattern recognition receptor signaling pathway →	-0.086	-1.693	<.001	.001	3	8
OVARY	Vertebrate eye-specific patterning →	-1.340	-1.292	.001	.002	3	8
SOFT_TISSUE	Regulation of angiogenesis →	-0.069	-1.453	.006	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,981 associations by consensus.

Response to interleukin-9 by CITED1 expression — LUNG_SCLC

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