CISH

Across TCGA patient cohorts, CISH RNA expression is significantly associated with the protein abundance of many other proteins, with 21,121 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CISH-associated proteins across cancer lineages are CAD, FBP1, and MYO1G. Each is linked with CISH in more than 5 cancer types. Because this analysis shows association rather than direction, both CISH-to-partner and partner-to-CISH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISH versus CAD in LSCC, with a Pearson correlation of -0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CISH→partner) and Y-score (partner→CISH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CAD →	-0.318	-0.764	<.001	<.001	3	6
LSCC	FBP1 →	+0.578	+0.648	<.001	<.001	3	6
GBM	MYO1G →	+0.614	+0.596	.002	.003	3	5
LSCC	XPOT →	-0.400	-0.639	<.001	<.001	3	5
BRCA	ABHD14B →	+0.379	+1.024	<.001	<.001	3	5
GBM	ALOX5 →	+0.711	+0.626	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,121 associations by consensus.

CISH vs CAD — LSCC

Explore this scatter interactively →