CISD3

Across TCGA patient cohorts, CISD3 RNA expression is significantly associated with the RNA expression of many other genes, with 18,960 significant associations in total. THYM shows the largest number of these associations.

The most reproducible CISD3-associated genes across cancer lineages are PSMB3, CENPX, and MRPL12. Each is linked with CISD3 in more than 33 cancer types. Because this analysis shows association rather than direction, both CISD3-to-partner and partner-to-CISD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CISD3 versus PSMB3 in DLBC, with a Pearson correlation of 0.72.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CISD3→partner) and Y-score (partner→CISD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
DLBC	PSMB3 →	+1.094	+0.933	<.001	<.001	3	34
DLBC	CENPX →	+0.978	+1.225	<.001	<.001	3	33
CHOL	MRPL12 →	+1.280	+1.005	<.001	<.001	3	33
ACC	GALK1 →	+1.290	+0.921	<.001	.002	3	33
ACC	TACO1 →	+0.799	+0.823	<.001	<.001	3	33
ACC	COA3 →	+0.953	+0.966	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,960 associations by consensus.

CISD3 vs PSMB3 — DLBC

Explore this scatter interactively →